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Biologists discover new strategy to treat central nervous system injury

Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. They also found that manipulating...

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Improved brain mapping tool 20 times more powerful than previous version

Salk Institute scientists have developed a new reagent to map the brain's complex network of connections that is 20 times more efficient than their previous version. This tool improves upon a technique...

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From retina to cortex: Unexpected division of labor

Neurons in our brain do a remarkable job of translating sensory information into reliable representations of our world that are critical to effectively guide our behavior. The parts of the brain that...

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Small brain area plays key role in making everyday decisions

Choosing what shirt to buy, what to order for lunch or whether to go with the hearty red wine or the lighter white all involve assigning values to the options. A small brain structure plays a central...

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The uncertain brain: Untangling ambiguity in neural circuits

Every day humans and animals face ambiguous circumstances. If we become sick after eating, we blame the food; however, if we then fall ill without having eaten that food, the causal link becomes...

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Scientists transform lower-body cells into facial cartilage

Caltech scientists have converted cells of the lower-body region into facial tissue that makes cartilage, in new experiments using bird embryos. The researchers discovered a "gene circuit," composed of...

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Refining optogenetic methods to map synaptic connections in the brain

Optogenetics is a technique that combines genetics and optics to control neuronal activity, which is based on the discovery of light-sensitive membrane channels within pond algae that control movement...

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A new window to understanding the brain

Scientists in recent years have made great strides in the quest to understand the brain by using implanted probes to explore how specific neural circuits work.

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Adverse effects of cannabis scientifically verified

Researchers have clarified important mechanisms involved in the formation of neural circuits in the brain. This group also discovered that delta-9-tetrahydrocannabinol (THC), a psychoactive substance...

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How brain separates relevant and irrelevant information

Imagine yourself sitting in a noisy café trying to read. To focus on the book at hand, you need to ignore the surrounding chatter and clattering of cups, with your brain filtering out the irrelevant...

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Positive and negative memories and behaviors are split up in the brains of mice

Like broccoli and ice cream on a toddler's plate, the brain also keeps nice and nasty information in separate places. Within the amygdala, an important memory center in the brain, pleasant experiences,...

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The power of expectation can restrain hyper-emotional memories in the brain

The creaking of an opening gate followed by a dog attack can disturb otherwise pleasant evening walks. The sound of that gate opening on subsequent walks will elicit an emotional response, and the...

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Biologists identify signals that drive distinct behavior in microscopic...

Dr. Kevin Collins carefully places a petri dish with what looks like a blotch of yellowish slime under a microscope. Magnified, the slime comes alive as hundreds of translucent worms, known as...

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Switching off the brain: Study implements an optogenetic tool that inhibits...

Switching off specific brain regions in a laboratory animal is an important type of experiment used to better understand how the brain works. A study published in Nature Methods by Singapore-based...

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A new brain mapping technique reveals circuitry of Parkinson's disease tremors

If a piece of electronics isn't working, troubleshooting the problem often involves probing the flow of electricity through the various components of the circuit to locate any faulty parts.

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Myopia cell discovered in retina

Northwestern Medicine scientists have discovered a cell in the retina that may cause myopia when it dysfunctions. The dysfunction may be linked to the amount of time a child spends indoors and away...

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Fighting blindness: Scientists bring a key protein into focus

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered how a protein called α2δ4 establishes proper vision. Their research helps explain why mutations in the gene...

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White House funds songbird study to unlock mystery of vocal learning

A young songbird sings an intricate melody from its caged perch, trying to echo the mating song heard so many times from his father.

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Boosting natural brain opioids may be a better way to treat anxiety

Boosting natural brain opioids may be a better way to treat disabling emotions, says new research revealing their role in regulating critical brain circuits affecting fear and anxiety.

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Neuroscientists rewire brain of one species to have connectivity of another

ATLANTA-Scientists at Georgia State University have rewired the neural circuit of one species and given it the connections of another species to test a hypothesis about the evolution of neural circuits...

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Coupling of movement and vision

In a study published in Cell, Georg Keller and his group shed light on neural circuits in the cortex that underlie the integration of movement and visual feedback. They identified a mechanism in the...

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How we recall the past: Neuroscientists discover a brain circuit dedicated to...

When we have a new experience, the memory of that event is stored in a neural circuit that connects several parts of the hippocampus and other brain structures. Each cluster of neurons may store...

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New research on Fragile X syndrome reinforces importance of early detection

Fragile X syndrome—the most common heritable cause of autism spectrum disorder—is something of a phantom. It interferes with the production of a protein critical to synapse formation during a brief...

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Proteins involved in brain's connectivity are controlled by multiple checkpoints

University of Bristol scientists have found that the delivery of a group of proteins involved in the information flow between the brain's nerve cells to the synapse is much more sophisticated than...

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A new genetic marker for schizophrenia

Schizophrenia is a complicated disease that often appears in early adulthood. Although scientists have not traced the genetic causes, more than 80% of schizophrenia cases are considered to have a...

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Neurobiologist studies how the brain learns to interpret what the body touches

It's a touchy subject—literally. Samuel Andrew Hires, assistant professor of biological sciences, wants to know how the brain learns to understand what we're touching. Understanding how this works...

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Exploring the neural mechanisms behind social decision-making, cooperation,...

Humans, primates, and many other animals are innately social, spending much of their lifetimes in the presence of other individuals, but little is known about the neural mechanisms that generate social...

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Autism-linked gene stunts developing dendrites

Increased expression of a gene linked to autism spectrum disorders (ASDs) leads to a remodeling of dendrites during brain development, according to a new study conducted in cultured neurons and an ASD...

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Songbirds may hold the secret to how babies learn to speak

The explanation for how people learn complex behaviors, such as speech, might be found in a new study of songbirds by scientists at the USC Dornsife College of Letters, Arts and Sciences.

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Finding the tipping point for sleep

Sleep is essential for many aspects of normal life, but how we actually fall asleep remains a mystery.

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